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Product Name | CAY10735 |
Description | An anticancer compound; inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.674-11.56 µM); inhibits migration of and EMT in A375 and B16/F10 melanoma cells in vitro in a concentration-dependent manner; reduces the viability of spheroid A375 and B16/F10 cells (IC50s = 3.04 and 1.24 µM, respectively) and increases production of ROS in these cells in a concentration-dependent manner; reduces tumor growth in B16/F10 melanoma and Lewis lung carcinoma mouse models and an A375 mouse xenograft model at 5 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | anti-cancer CAY-10735 A-375 B-16 F-10 Compound 48 Compound48 |
Gene, Accession, CAS # | CAS: 2251753-58-7 |
Catalog # | 26753-10 |
Price | $826.00 |
Order / More Info | CAY10735 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |