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Product Name | VU0119498 |
Description | An M1, M3, and M5 muscarinic receptor positive allosteric modulator (EC50s = 6.04, 6.38, and 4.08 µM, respectively, in calcium mobilization assays); selective for M1, M3, and M5 mAChRs over M2 and M4 mAChRs in CHO cells expressing the human receptors; enhances ACh-induced insulin secretion in MIN6-K8 pancreatic β-cells at 20 µM; decreases glucose tolerance and increases insulin secretion in mice fed normal chow, as well as in a mouse model of high-fat diet-induced obesity, at 0.5 mg/kg |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | VU-0119498 VUo119498 VUo-119498 MIN6K8 M-1 5 Z 57823200 Z57823200 N-Bromobenzylisatin Bromobenzyl) Bromobenzyl)indole Bromobenzyl)indoline dihydro Bromophenyl)methyl]indole |
Gene, Accession, CAS # | CAS: 79183-37-2 |
Catalog # | 36132-100 |
Price | $191.00 |
Order / More Info | VU0119498 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |