CAY10744 from CAYMAN CHEMICAL COMPANY
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| Product Name | CAY10744 |
| Description | A topoisomerase II-α poison; inhibits topoisomerase II-α by 78.9% at 20 µM; selective for topoisomerase II-α over topoisomerase I providing 100 and 0% inhibition, respectively, at 100 µM; inhibits proliferation of HCT15, T47D, DU145, and HeLa cancer cells (IC50s = 0.014, 0.00267, 0.072, and 2.46 µM, respectively); induces apoptosis in T47D cells at 10 and 30 µM; reduces tumor growth in an MDA-MB-231 orthotopic mouse model of breast cancer at 12 mg/kg per day |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CAY 10744 IIα HCT 15 T47 D T-47D 47 DU 145 MDAMB231 MDAMB MB231 |
| Gene, Accession, CAS # | CAS: 2375613-31-1 |
| Catalog # | 29802-10 |
| Price | $437.00 |
| Order / More Info | CAY10744 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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