VX-765 from CAYMAN CHEMICAL COMPANY

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Product NameVX-765
DescriptionA prodrug form of VRT-043198; inhibits LPS-induced increases in serum IL-1β levels in mice at 50, 100, and 200 mg/kg; reduces oxazolone-induced ear edema and levels of IL-1β, IL-18, and IFN-γ in ear tissue in an oxazolone-sensitized mouse model of delayed-type hypersensitivity; reduces forepaw inflammation in a mouse model of collagen-induced arthritis in a dose-dependent manner; decreases seizure duration and the number of seizures in a mouse model of acute seizures induced by hippocampal kainic acid injection at ≥50 mg/kg, as well as delays the onset of seizures at 100 and 200 mg/kg; reduces the aggregated duration of epileptic activity in a mouse model of chronic epilepsy
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesBelnacasan
Gene, Accession, CAS #CAS: 273404-37-8
Catalog #28825-10
Price$104.00
Order / More InfoVX-765 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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