SU 9516 from CAYMAN CHEMICAL COMPANY
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| Product Name | SU 9516 |
| Description | A potent inhibitor of several CDKs with selectivity for Cdk2 (IC50s = 22, 40, and 200 nM for Cdk2/cyclin A, Cdk1/cyclin B, and Cdk4/cyclin D1); has anti-proliferative and pro-apoptotic activity in tumor cells |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Cdk2 apoptosis cancers cyclins inhibitors leukemias pRb retinoblastomas proteins cells cycles SU9516 SU-9516 SU 9515 3-substituted indolinones 3 substituted anti-proliferatives anti proliferatives antiproliferatives pro-apoptotic proapoptotic pro apoptotic activity activities active tumors cyclin-dependent dependent kinases CDKs Cdk-2 2 two Cdk1 Cdk-1 1 one A B D1 cyclin-D1 cyclin-A cyclin-B retinoblastomas pRb cell-cycles arrests U-937 U 937 U937 jurkat HL-60 HL60 HL 60 Mcl1 Mcl-1 Mcl 1 mitochondrial mitochondrias injuries injury deaths inhibits inhibitions Cdk4 Cdk-4 4 Cdk2/cyclin Cdk1/cyclin Cdk4/cyclin 3 three substituted PKC p38 PDGFR EGFR phosphorylations pRb/E2F complexes formations downregulates downregulation transcriptions |
| Gene, Accession, CAS # | CAS: 377090-84-1 |
| Catalog # | 14796-5 |
| Price | $93.00 |
| Order / More Info | SU 9516 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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