Edit |   |
---|---|
Product Name | A-485 |
Description | A p300/CBP inhibitor (IC50 = 60 nM); decreases H3K27Ac levels in PC3 cells; reduces proliferation of various tumor cell lines; inhibits expression of PSA and H3K27Ac occupancy at the PSA enhancer in LNCaP-FGC cells; reduces tumor volume in a LuCaP-77 mouse xenograft model of castration-resistant prostate cancer at 100 mg twice per day for 21 days |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | A485 H-3-K-27-Ac H3-K27Ac H3K-27Ac H3K27 3K27Ac H3K9 9Ac PC-3 NSC-LC nonHodgkin's LNCaPFGC LuCaP77 acetyl transferase P-300 H-3 |
Gene, Accession, CAS # | CAS: 1889279-16-6 |
Catalog # | 24119-5 |
Price | $190.00 |
Order / More Info | A-485 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |