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Product Name | Derenofylline |
Description | An adenosine A1 receptor antagonist (Ki = 1 nM); selective for adenosine A1 over A2A, A2B, and A3 receptors (Kis = 398, 3,981, and 200 nM, respectively); decreases adenosine A1 receptor-mediated adenosine-induced bradycardia in rats (ED50 = 0.49 mg/kg) but reduces A2 receptor-mediated adenosine-induced hypotension by only 44.6% at an intravenous dose of 5 mg/kg; prevents increases in heart levels of collagen I and III in nephrectomized rats at 10 mg/kg per day; reduces relative plaque counts in a Zika virus plaque-forming assay in A549 cells (IC50 = 58.6 nM) in an adenosine A1 receptor-independent manner |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | SLV 320 |
Gene, Accession, CAS # | CAS: 251945-92-3 |
Catalog # | 27666-25 |
Price | $371.00 |
Order / More Info | Derenofylline from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |