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Product Name | Bexarotene |
Description | An RXR agonist (EC50s = 28, 25, and 20 nM for RXRα, RXRβ, and RXRγ, respectively, in reporter assays); selective for RXRs over RARs (RARs; EC50s = >10 µM for RXRα, RXRβ, and RXRγ); induces apoptosis in MJ, HuT 78, and HH CTCL cells at 10 µM; inhibits lung metastasis and angiogenesis in A549 and MDA-MB-231 mouse xenograft models at 100 mg/kg per day; reduces viral load in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC90 = 9.4 µM) and inhibits SARS-CoV-2 replication in a plaque reduction assay (EC50 = 2.01 µM) |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | LG 100069|LGD 1069|Ro 26-4455|SR 11247 |
Gene, Accession, CAS # | CAS: 153559-49-0 |
Catalog # | 11571-25 |
Price | $68.00 |
Order / More Info | Bexarotene from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |