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Product Name | VTX-27 |
Description | A PKCθ inhibitor (Ki = 0.08 nM); selective for PKCθ over PKCα, -βI, -βII, -γ, -δ, -ε, -η, -μ, and -ζ (Kis = 1->5,000 nM) as well as a panel of seven kinases from the Src, Syk, Tec, and MAP kinase families (Kis = >1,000 nM for all); inhibits CD28-induced IL-2 release in isolated human PBMCs (IC50 = 11 nM); prevents staphylococcal enterotoxin B-induced increases in IL-2 plasma levels in mice at 12.5, 25, and 50 mg/kg, p.o. |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | VTX27 PKC θ PKC α cd 28 IL2 peripheral blood mononuclear cell |
Gene, Accession, CAS # | CAS: 1321924-70-2 |
Catalog # | 36938-500 |
Price | $96.00 |
Order / More Info | VTX-27 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |