Chebulagic Acid from CAYMAN CHEMICAL COMPANY

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Product NameChebulagic Acid
DescriptionA polyphenol and tannin with diverse biological activities; an inhibitor of COX-1, COX-2, and 5-LO (IC50s = 15, 0.92, and 2.1 µM, respectively) as well as α-glucosidase and 15-LO (IC50s = 0.05 and 24.9 µM, respectively); inhibits LPS-induced increases in iNOS, COX-1, COX-2, and 5-LO protein levels, production of NO, PGE2, and ROS, and nuclear translocation of NF-κB in RAW 264.7 macrophages; inhibits the growth of HCT15, COLO 205, MDA-MB-231, DU145, and K562 cancer cells (GI50s = 20.3, 18, 26.2, 28.54, and 30.66 µM, respectively); increases insulin-stimulated glucose uptake in 3T3-L1 adipocytes; scavenges DPPH radicals (IC50 = 1.4 µM); exhibits antiviral activity against cytomegalovirus, hepatitis C virus, dengue virus, measles virus, and respiratory syncytial virus in vitro (EC50s = 25.5, 12.16, 13.11, 34.42, and 0.38 µM, respectively)
Size10 mg
Concentrationn/a
Applicationsn/a
Other Names19293-38-0 Terminalia COX1 COX2 5LO 15LO NFκB RAW264.7 HCT 15 COLO205 DU145 K 562 3T3L1 anti-viral MDAMB231
Gene, Accession, CAS #CAS: 23094-71-5
Catalog #25203-10
Price$866.00
Order / More InfoChebulagic Acid from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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