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Product Name | Collectin-10, Human, ELISA |
Description | Range: 0.4 to 25 ng/ml. The complement system is the first line of defense against pathogens and important component of innate as well as adaptive immunity. The three major pathways of innate immunity are the classical, alternative and lectin pathway. Each pathway is activated in a different way. The lectin pathway recognizes foreign carbohydrates structures via MBL, ficolins and collectins. Collectin-10 (collectin liver 1/CL-L1), CL-K1 (collectin kidney 1/Collectin-11) and CL-P1 (collectin placenta 1/Collectin-12) are most recently discovered. Collectin-10 and Collectin-11 are quite homolog, have a classical collectin structure and are highly conserved in mammals. Collectin-10 and Collectin-11 can bind to carbohydrate ligands and DNA of pathogens or on the membrane of damaged cells. They interact with MASPs and activate in a similar way to MBL and ficolins the lectin pathway. Native Collectin-10 displays a calcium dependent binding pattern. A conformational change in carbohydrate reco |
Size | 1 x 96 det. |
Concentration | n/a |
Applications | RUO |
Other Names | Collectin liver protein 1; CL-L1; Collectin-34; CL-34 |
Gene, Accession, CAS # | n/a |
Catalog # | HK364-01 |
Price | $1054 |
Order / More Info | Collectin-10, Human, ELISA from HYCULT BIOTECH |
Product Specific References | n/a |