Alpha-1-antitrypsin, Human, ELISA kit from HYCULT BIOTECH
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| Product Name | Alpha-1-antitrypsin, Human, ELISA kit |
| Description | Range: 1.6 to 100 ng/ml. The human alpha-1 antitripsin ELISA detects both the healthy monomeric form (M variant) and the disease associated polymeric forms (Z variants) of human alpha-1-antitrypsin with equal affinity. Alpha-1-antitrypsin is a member of the serine protease inhibitor (serpin) superfamily which are proteins known for their ability to inhibit proteases. It is the most abundant circulating protease inhibitor known. It mainly targets enzymes released by neutrophils, especially neutrophil elastase (NE) but also proteinase 3 (PR3) and Cathepsin G (CG). Serpinopathies are conformational diseases characterized by the polymerization and intracellular retention of members of the serpin superfamily. The best known is Alpha-1-antitrypsin deficiency, with the most common severe deficiency allele being the Z mutation (Glu342Lys). This severe autosomal dominant disorder causes the protein to undergo a conformational transition and form ordered polymers that are retained within hepatoc |
| Size | 2 x 96 det. |
| Concentration | n/a |
| Applications | RUO |
| Other Names | Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1 |
| Gene, Accession, CAS # | n/a |
| Catalog # | HK387-02 |
| Price | $1702 |
| Order / More Info | Alpha-1-antitrypsin, Human, ELISA kit from HYCULT BIOTECH |
| Product Specific References | n/a |
HYCULT BIOTECH
HYCULT BIOTECH
Frontstraat 2a
5405 PB Uden THE NETHERLANDS
P: +31 (0)413 251335
F: +31 (0)413 248353
info@hycultbiotech.com
https://www.hycultbiotech.com
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