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Product Name | Beta-defensin 2, Human, Peptide |
Description | Antimicrobial proteins (AMP) are a fundamental element of the primary response against pathogens. AMP's are small endogenous cationic molecules expressed by phagocytic and epithelial cells. The antimicrobial activity of AMP's is directed towards a broad spectrum of pathogens, like Gram-positive and -negative bacteria, viruses, yeast and fungi. AMP's aid in innate immunity and adaptive immunity via direct inactivation and by immunomodulatory activity like leukocyte migration. Defensins are the most prominent mammalian AMP's. Three defensin peptide families are identified, the α-, β-, and θ-defensins. They are characterized by a triple-stranded β-hairpin structure, six disulfide-linked cysteine residues and a positive charge. They are synthesized as preproteins and undergo processing to become a fully active peptide. Defensins are divided in alpha- and beta-defensins depending on their disulfide bridging pattern. Human beta-defensin-2 (hBD-2) is a cystein-rich catio |
Size | 50 µg |
Concentration | n/a |
Applications | Functional studies, Western blot. RUO |
Other Names | HBD2 |
Gene, Accession, CAS # | n/a |
Catalog # | HC2140-50UG |
Price | $409 |
Order / More Info | Beta-defensin 2, Human, Peptide from HYCULT BIOTECH |
Product Specific References | n/a |