Edit |   |
---|---|
Product Name | C3, Mouse, ELISA |
Description | Range: 31.3 to 2000 ng/ml. The C3 and C5 convertases are enzymatic complexes that initiate and amplify the activity of the complement pathways and ultimately generate the cytolytic MAC. The synthesis of C3 is tissue-specific and is modulated in response to a variety of stimulatory agents. After cleavage by C3 convertase the anaphylotoxin C3a and activating C3b are formed. When bound to the cell surface C3b forms the start of the terminal pathway of complement by initiating the formation of the C5 convertase. C3 has a molecular weight of app. 185kDa and is the most abundant protein of the complement system with serum protein levels of about 1.3 mg/ml. C3 is primarily produced by the liver but is also generated in macrophages, neutrophils, endothelial end epithelial cells. Due to the high levels in circulation with low biological reactivity, C3 is able to act in a fast and potent way when danger by eg pathogens is encountered. Defects in C3 can be unfavorable to the host leading to recur |
Size | 1 x 96 det. |
Concentration | n/a |
Applications | Immuno assays. RUO |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | HK2002-01 |
Price | $1054 |
Order / More Info | C3, Mouse, ELISA from HYCULT BIOTECH |
Product Specific References | n/a |