Edit |   |
---|---|
Product Name | C3b, Mouse, ELISA kit |
Description | Measurable concentration range of 3.2 to 200 AU/ml. The mouse C3b ELISA assay is specific for the cleaved C3 fragments C3b, iC3b, and C3c, and for activated C3. The complement system is an important component of innate immunity. Complement-derived products mediate functions contributing to pathogen killing and elimination. However, inappropriate activation of the system contributes to the pathogenesis of immunological and inflammatory diseases. Complement component 3 (C3) occupies a central position because of the manifold biological activities of its activation fragments, including the major fragment, C3b, which anchors the assembly of convertases effecting C3 and C5 activation. C3 is converted to C3b by proteolysis of its anaphylatoxin domain, by either of two C3 convertases. This activates a stable thioester bond, leading to the covalent attachment of C3b to cell-surface or protein-surface hydroxyl groups through transesterification. C3b is further cleaved into iC3b, C3c, C3dg and C |
Size | 1 x 96 det. |
Concentration | n/a |
Applications | RUO |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | HK216-01 |
Price | $1054 |
Order / More Info | C3b, Mouse, ELISA kit from HYCULT BIOTECH |
Product Specific References | n/a |