CD8 Antibody Kit, anti-human, FITC, REAlease® from MILTENYI BIOTEC B.V. & Co. KG
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| Product Name | CD8 Antibody Kit, anti-human, FITC, REAlease® |
| Description | CD8 Antibody Kit, anti-human, FITC, REAlease®. Clone REAL100 is an antibody fragment derived from the full CD8 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL100 recognizes the alpha chain of the human CD8 antigen, a cell-surface glycoprotein also known as Leu-2 or CD8a. CD8 is strongly expressed on human cytotoxic T cells and thymocytes as well as on a subset of NK cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8α homodimer or as a CD8α/β heterodimer. CD8 acts as a co-receptor for the T cell receptor and binds to the MHC class I molecules. CD8 is involved in T cell development and activation of mature T cells. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes. |
| Size | 100 tests |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Other Names | Leu-2, CD8a, MAL, p32, Cd8b1, LY3, Lyt3, P37, Ly-2 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 130-122-718 |
| Price | $375 |
| Order / More Info | CD8 Antibody Kit, anti-human, FITC, REAlease® from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Devine, L. et al. (1999) Orientation of the Ig domains of CD8 alpha beta relative to MHC class I. J Immunol 162 (2): 846-851. | Gao, G. F. et al. (2000) Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor. Immunol. Today 21 (12): 630-636. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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