Human CellExp IL-6 Ralpha, Human Recombinant from MYBIOSOURCE INC.
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| Product Name | Human CellExp IL-6 Ralpha, Human Recombinant |
| Description | Purity ≥98%. Background: IL-6 mediates its biological effects through the type I IL-6 receptor system that consists of two chains, IL-6Ralpha and gp130. The IL-6Ralpha chain is the binding component specific to IL-6; while the gp130 only transmits signals of IL-6 when bound to IL-6Ralpha. The gp130 also can transmit signals from LIF, OSM, CNTF, IL-11 and CT-1 in conjunction with other receptor subunits. The low-affinity binding site for IL-6 is composed of IL-6Ralpha alone. IL-6Ralpha is expressed in a wide range of cells including T cells, fibroblasts and macrophages. Soluble IL-6Ralpha which consists of only the extracellular domain of the IL-6Ralpha chain, acts as an agonist of IL-6 activity at low concentrations. Recombinant human sI. MW: ~37.6 kDa |
| Size | 0.01 mg, 0.05 mg |
| Concentration | n/a |
| Applications | SDS-PAGE; HPLC |
| Other Names | [soluble IL-6 receptor alpha; B cell stimulatory factor-2; CD126], [IL6R; IL6R; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; gp80] |
| Gene, Accession, CAS # | [IL6RA], Gene ID: 3570, NCBI: NP_000556.1, UniProt: P08887 |
| Catalog # | MBS844275 |
| Price | $200, $750 |
| Order / More Info | Human CellExp IL-6 Ralpha, Human Recombinant from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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