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Product Name | AAL-993 |
Description | Purity >98% (TLC: 5% CH3OH/CH2Cl2; Rf=0.46); NMR conforms. VEGF inhibitor. Potent inhibitor of Cdk5/p25 (IC50=64 nM). Inhibits Cdk2/cyclin E at slightly higher concentration (IC50=98nM)1. Protects cells against NAC-amyloid-induced cell death2. Cell permeable. Scientific Background: A potent and selective inhibitor of VEGFR-1 (IC50=130nM), VEGFR-2 (IC50 |
Size | 5 mg, 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 269390-77-4 |
Catalog # | MBS515037 |
Price | $260, $765 |
Order / More Info | AAL-993 from MYBIOSOURCE INC. |
Product Specific References | 1. CJ Helal et al. Bioorg. Med. Chem. Lett. 2004 14:55212. A Kazmierczak et al. Neurochem. Int. 2011 58:206 |