GSK3beta, Active from MYBIOSOURCE INC.
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| Product Name | GSK3beta, Active |
| Description | Sequence: Full Length. Description: Recombinant full-length human GSK3beta was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. Scientific Background: GSK3beta is a serine threonine protein kinase that was originally identified as the kinase that phosphorylate and inhibits glycogen synthase (1). GSK3beta is ubiquitously present in human tissues and implicated in the regulation of several physiological processes, including the control of glycogen and protein synthesis by insulin, modulation of the transcription factors AP-1 and CREB. Transient transfection of human GSK3 beta into Chinese hamster ovary cells stably transfected with individual human tau isoforms leads to hyperphosphorylation of tau at all the sites inv. MW: ~73 kDa |
| Size | 0.005 mg, 0.01 mg |
| Concentration | n/a |
| Applications | Kinase Assay, Western Blot (WB) |
| Other Names | [Homo sapiens glycogen synthase kinase 3 beta (GSK3B), transcript variant 1, mRNA; Glycogen synthase kinase-3 beta; glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta; Serine/threonine-protein kinase GSK3B (EC:2.7.11.1)], [GSK3B; GSK3B; GSK-3 beta] |
| Gene, Accession, CAS # | [GSK3beta], Gene ID: 2932, NCBI: NM_002093.3 |
| Catalog # | MBS515505 |
| Price | $310, $405 |
| Order / More Info | GSK3beta, Active from MYBIOSOURCE INC. |
| Product Specific References | 1. Sutherland C. et al: Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling. Biochem J. 1993 Nov 15;296 (Pt 1):15-9. 2. Sperber BR, Leight S, Goedert M, Lee VM. Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells. Neurosci Lett. 1995 Sep 8;197 (2):149-53. |
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