Recombinant TNF-alpha from MYBIOSOURCE INC.

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Product NameRecombinant TNF-alpha
DescriptionSequence: 78-234aa. Purity >90% by SDS-PAGE. TNF-alpha, also known as tumor necrosis factor, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, apoptosis, and immune system development. This protein is produced by a wide variety of immune and epithelial cell types. It is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface. Cell surface TNF can induce the lysis of neighboring tumor cells and virus infected cells, and it can generate its own downstream cell signaling following ligation by soluble TNFR I. It also promotes inflammatory responses by inducing the activation of vascular endothelial cells and macrophages. Re. MW: 17.5 kDa (158aa) confirmed by MALDI-TOF
Size0.02 mg, 0.1 mg
Concentration1mg/ml (determined by Bradford assay)
ApplicationsBioactivity, SDS-PAGE
Other Names[Tumor necrosis factor; TNF-a; TNF; TNFa], [TNF; TNF; TNFa; TNF-a; TNF-alpha; TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2]
Gene, Accession, CAS #[TNF-alpha], Gene ID: 280943, NCBI: NP_776391.2, UniProt: Q06599
Catalog #MBS201122
Price$255, $485
Order / More InfoRecombinant TNF-alpha from MYBIOSOURCE INC.
Product Specific ReferencesBojarojc-Nosowicz B., et al (2015). Pol J Vet Sci. 18(3): 533-9. Lendez PA., et al (2015). Arch Virol. 160(8): 2001-7.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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