Recombinant Human respiratory syncytial virus A Fusion glycoprotein F0 (F), partial from MYBIOSOURCE INC.

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Product NameRecombinant Human respiratory syncytial virus A Fusion glycoprotein F0 (F), partial
DescriptionSequence: 27-529aa. Purity >85% as determined by SDS-PAGE. During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2. Interacts directly with heparan sulfate and may participate in virus attachment. Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity. Later in infection, proteins F expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigge. MW: 60.8 kDa
Size0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli)
Concentrationn/a
Applicationsn/a
Other Names[Fusion glycoprotein F0; Fusion glycoprotein F0]
Gene, Accession, CAS #[F], NCBI: P11209.2, UniProt: P11209
Catalog #MBS7110919
Price$200, $260, $430
Order / More InfoRecombinant Human respiratory syncytial virus A Fusion glycoprotein F0 (F), partial from MYBIOSOURCE INC.
Product Specific ReferencesStructural characterization of the human respiratory syncytial virus fusion protein core. Zhao X., Singh M., Malashkevich V.N., Kim P.S.Proc. Natl. Acad. Sci. U.S.A. 97:14172-14177 (2000)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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