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Product Name | Porcine TNF-alpha |
Description | Purity > 95% by SDS-PAGE and RP-HPLC. Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF1A, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, apoptosis, and immune system development. TNF-alpha is produced by a wide variety of immune and epithelial cell types. Human TNF-alpha consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD). Within the ECD, human TNF-alpha shares 97% aa sequence identity with rhesus and 71% - 92% with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-alpha. The 26 kDa type 2 transmembrane protein is assembled intracellularly to form a. MW: 17.2 kDa |
Size | 0.02 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [Recombinant Porcine TNF-alpha], [TNF; TNF; TNFa; TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2] |
Gene, Accession, CAS # | [TNF-alpha], Gene ID: 397086, NCBI: NP_999187.1, UniProt: P23563 |
Catalog # | MBS692048 |
Price | $340 |
Order / More Info | Porcine TNF-alpha from MYBIOSOURCE INC. |
Product Specific References | n/a |