PCBP1, 1-163aa, Human, His tag, E Coli from MYBIOSOURCE INC.
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| Product Name | PCBP1, 1-163aa, Human, His tag, E Coli |
| Description | Purity > 85% by SDS-PAGE. PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is. MW: 19.6 kDa (186aa) confirmed by MALDI-TOF |
| Size | 0.1 mg, 0.5 mg |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | [Poly (rC) binding protein 1; Poly (rC) binding protein 1; hnRNP-E1; hnRNP-X; HNRPE1; HNRPX], [PCBP1; PCBP1; HNRPX; HNRPE1; hnRNP-X; HEL-S-85; hnRNP-E1; hnRNP E1] |
| Gene, Accession, CAS # | [PCBP1], Gene ID: 5093, NCBI: NP_006187, UniProt: Q15365 |
| Catalog # | MBS205177 |
| Price | $310, $720 |
| Order / More Info | PCBP1, 1-163aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
| Product Specific References | Beausoleil S.A., et al. (2006) Nat. Biotechnol. 24:1285-1292; Yu L.-R., et al. (2007) J. Proteome Res. 6:4150-4162; |
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