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Product Name | CFD, 21-253aa, Human, His tag, Baculovirus |
Description | Purity > 95% by SDS-PAGE. CFD, also known as Complement factor D preproprotein, is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. There are two antiparallel beta-barrel domains with each barrel containing six beta-strands with the same typology in all enzymes. The major difference in backbone structure between Factor D and the other serine proteases of the chymotrpsin family is in the surface loops connecting the secondary structural elements. Factor D displays different conformations of major catalytic and substrate-binding residues typically found in the chrotrypsin family. Recombinant human CFD, fused to His-tag at C-terminus, was expressed in insect cell and purifi. MW: 26.01kDa (241aa) confirmed by MALDI-TOF 28-40kDa (SDS-PAGE under reducing conditions.) |
Size | 0.05 mg, 0.25 mg |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | [Complement factor D preproprotein; ADIPSIN; ADN; DF; PFD], [CFD; CFD; DF; ADN; PFD; ADIPSIN; DF; PFD] |
Gene, Accession, CAS # | [CFD], Gene ID: 1675, NCBI: NP_001919, UniProt: P00746 |
Catalog # | MBS205939 |
Price | $310, $925 |
Order / More Info | CFD, 21-253aa, Human, His tag, Baculovirus from MYBIOSOURCE INC. |
Product Specific References | Ronti T. et al. (2006) Clin. Endocrinol. 64 (4):355-65.; Volanakis JE. et al. (1996). Protein Sci. 5 (4):553-64. |