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Product Name | A-1155463 |
Description | Purity >98%. A-1155463 is a highly potent and selective BCL-XL inhibitor, A-1155463 shows picomolar binding affinity to BCL-XL (Ki 1000-fold weaker binding to BCL-2 (Ki = 80 nM) and related proteins BCL-W (Ki = 19 nM) and MCL-1 (Ki > 440 nM). MW: 669.79 |
Size | 5 mg, 10 mg, 50 mg |
Concentration | 0.1 mM: 14.93 mL (1 mg); 74.65 mL (5 mg); 149.3mL (10 mg). 0.5 mM: 2.99 mL (1 mg); 14.93 mL (5 mg); 29.86 mL (10 mg). 1 mM: 1.49 mL (1 mg); 7.47 mL (5 mg); 14.93 mL (10 mg). 5 mM: 0.3 mL (1 mg); 1.49 mL (5 mg); 2.99 mL (10 mg) |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 1235034-55-5 |
Catalog # | MBS384082 |
Price | $180, $255, $915 |
Order / More Info | A-1155463 from MYBIOSOURCE INC. |
Product Specific References | Chauhan D,.et al. BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1 Maturation in Macrophages, Cell Rep, 2018, Nov 27;25(9):2354-2368.e5 PMID: 30485805 |