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Product Name | CD4 Fragment Recombinant Protein |
Description | Purity ~90%. CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response (1). On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120 (2). This soluble CD4 fragment (sCD4) will work in HIV neutralization assays at levels c. MW: 27 kDa (Calculated) |
Size | 0.05 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), MS |
Other Names | [CD4 Antibody : CD4mut; CD4 molecule], [CD4; CD4; CD4mut] |
Gene, Accession, CAS # | [CD4], Gene ID: 920, NCBI: NP_000607, UniProt: P01730 |
Catalog # | MBS153293 |
Price | $270 |
Order / More Info | CD4 Fragment Recombinant Protein from MYBIOSOURCE INC. |
Product Specific References | n/a |