Edit |   |
---|---|
Product Name | A-966492 |
Description | A-966492 is a highly potent and efficacious poly(ADP-ribose) polymerase (PARP) inhibitor with a Ki and EC50 of 1 nM. In addition, it is orally bioavailable across multiple species, crosses the blood-brain barrier, and appears to distribute into tumor tissue. It also demonstrated good in vivo efficacy in a B16F10 subcutaneous murine melanoma model in combination with temozolomide and in an MX-1 breast cancer xenograft model both as a single agent and in combination with carboplatin. [1]. MW: 324.35 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | [A-966492] |
Catalog # | MBS8506196 |
Price | $1135 |
Order / More Info | A-966492 from MYBIOSOURCE INC. |
Product Specific References | n/a |