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Product Name | Human CellExpCD4, Human Recombinant |
Description | Purity ≥98%. Background: Cluster of Differentiation 4 (CD4), also known as T-cell surface antigen T4/Leu-3 (LEU-3) and CD4mut, is a single-pass type I membrane glycoprotein, and is a member of the immunoglobulin superfamily. CD4 expressed on the surface of T helper cells, monocytes, macrophages, and dendritic cells. It has four immunoglobulin domains (D1 to D4) that are exposed on the extracellular surface of the cell: D1 and D3 resemble immunoglobulin variable (IgV) domains. D2 and D4 resemble immunoglobulin constant (IgC) domains. CD4 is a co-receptor that assists the T cell receptor (TCR) with an antigen-presenting cell. Using its portion that resides inside the T cell, CD4 amplifies the signal generated by the TCR by recruiting an en. This protein rhCD4 is fused with Fc fragment of human IgG1 at the C-terminus, has a calculated MW of 68 kDa expressed. The predicted N-terminus is Lys26. Protein migrates as 80 kDa in reduced SDS-PAGE due to glycosylation. |
Size | 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | [CD4; CD-4; CD4mut; CD-4mut], [CD4; CD4; CD4mut] |
Gene, Accession, CAS # | [CD4], Gene ID: 920, NCBI: NP_000607.1, UniProt: P01730 |
Catalog # | MBS844333 |
Price | $250, $675 |
Order / More Info | Human CellExpCD4, Human Recombinant from MYBIOSOURCE INC. |
Product Specific References | n/a |