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Product Name | BCAS2 cDNA |
Description | BCAS2, also known as pre-mRNA-splicing factor SPF27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. It is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligand-independent manner) with TRbeta (thyroid hormone receptor beta), ERalpha (estrogen receptor alpha), ERbeta, PR (progesterone receptor) and PPARgamma (peroxisome proliferator-activated receptor gamma). This protein functions as an ER co-activator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer. This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector. |
Size | 10ug |
Concentration | n/a |
Applications | n/a |
Other Names | DAM1, Snt309, SPF27 |
Gene, Accession, CAS # | NCBI: NP_005863.1 |
Catalog # | ATGD0062 |
Price | $99 |
Order / More Info | BCAS2 cDNA from NKMAX Co. Ltd. |
Product Specific References | n/a |