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Product Name | BAG4 cDNA |
Description | BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector. |
Size | 10ug |
Concentration | n/a |
Applications | n/a |
Other Names | BAG-4, SODD, BAG family molecular chaperone regulator 4, BAG cochaperone 4, BCL2 associated athanogene 4 |
Gene, Accession, CAS # | NCBI: NP_004865.1 |
Catalog # | ATGD0089 |
Price | $99 |
Order / More Info | BAG4 cDNA from NKMAX Co. Ltd. |
Product Specific References | n/a |