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Product Name | Human CD93 - C1qR ELISA Kit |
Description | Specificity: Natural and recombinant human CD93. There is no detectable cross-reactivity with other relevant proteins. CD93 (Cluster of Differentiation 93) is a protein that in humans is encoded by the CD93 gene. CD93 belongs to the Group XIV C-Type lectin family and is mapped to 20p11.21. The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. It has also showed that this receptor is a positive marker for all bone marrow-repopulating stem cells because it is expressed on both CD34-negative and CD34-positive stem cells from umbilical cord blood and adult bone marrow. In addition, highly purified lineage-negative cells with the CD93 protein not only have bone marrow-repopulating capacity but also can differentiate into human hepatocytes in vivo. |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | C1q receptor 1, C1q/MBL/SPA receptor, C1qR, C1qR(p), C1qr1, C1QR1_HUMAN, C1qRp, CD93, CD93 antigen, CD93 molecule, CDw93, Complement component 1 q subcomponent receptor 1, Complement component C1q receptor, dJ737E23.1, ECSM3, Matrix remodeling associated protein 4, Matrix remodelling associated 4, Matrix-remodeling-associated protein 4, MXRA4 |
Gene, Accession, CAS # | CD93, Gene ID: 22918, NCBI: NP_036204.2, UniProt: Q9NPY3 |
Catalog # | KOA0792 |
Price | $639 |
Order / More Info | Human CD93 - C1qR ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |