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Product Name | Apicidin |
Description | Potent inhibitor of histone deacetylase (HDAC) activity and proliferation. Induces cell cycle arrest at the G1 phase. At 100nM it induces a long lasting hyperacetylation of histone H4 while that induced by trichostatin is transient. Stimulates apoptosis. Apoptosis is induced via induction of Fas/Fas ligand. Displays potent antiangiogenic effects and dramatically decreases HIF-1a protein levels and transcriptional activity in human and mouse tumor cell lines. Apicidin is a fungal toxin that has broad spectrum activity against Apicomplexan parasites |
Size | 5 mg |
Concentration | 5 mg |
Applications | Activator or Inhibitor |
Other Names | HDAC inhibitor |
Gene, Accession, CAS # | n/a |
Catalog # | P011-5MG |
Price | $366.24 |
Order / More Info | Apicidin from ARBOR ASSAYS, INC. |
Product Specific References | n/a |
Direct Order Fax Line: 734-677-6860